Antibody Identity card
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TOX2 Antibody
Protein information
TOX2 is a member of the Thymocyte selection-related HMG box protein family that shares structural similarities with TOX, TOX3 and TOX4. While TOX is linked to T cell exhaustion, TOX2 exhibits diverse functions, playing a critical role in human natural killer (NK) cell maturation by positively regulating T-box transcription factor (TBX21) expression. Additionally, TOX2 modulates T follicular helper (Tfh) cell differentiation and maintenance, regulating a set of Tfh-associated genes by activating their chromatin accessibility.
Protein link information
GeneCards General information
Uniprot TOX2 protein information
BioGps Database of gene expression profile of human TOX2
Protein Atlas TOX2 expression profile in human tissues on mRNA and protein level
Validation / characterisation
- Working
- No conclusive
- Not working
- Not tested
- CLONE NAME
- APPLICATIONS
Applications legend
- WB: Western blotting
- ICC: Immunocytochemistry
- IHC-P: Immunohistochemistry - Paraffin
- IF-F: Immunoflourescence - Frozen
- IF-P: Immunoflourescence - Paraffin
- FLOW: Flow cytometry
- IHC-P Species: Immunohistochemistry - Paraffin Species